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Geralmente, as doses variam de 500 mg a 2 g por dia

The expression of malondialdehyde (MDA) H 2 O 2 was significantly increased in the paw tissue of CIA mice, and intervention with curarelinone, the active ingredient of bitter ginseng, significantly inhibited oxidative damage and decreased the phosphorylation levels of signal transducer and activator of transcription (STAT)1, STAT3, and ratio of Th1 and Th17 cells in lymph nodes (62)

There is speculation that MGF may inhibit fibrosis by suppressing the expression of type I and III collagen, which are said to be key components of the extracellular matrix involved in fibrotic tissue development